Alpha-1 Antitrypsin Select

• Cat#No#: Al-343C
• Product Overview: Affinity chromatography resin with high selectivity for efficient industrial purification of alpha-1 antitrypsin (AAT).
  Outstanding pressure and flow rates reduce process times and improve process economy.
  Mild elution conditions at neutral pH The hydrophilic nature of the base matrix ensures low levels of non-specific binding.
• Description: Alpha-1 Antitrypsin Select is a packed-bed affinity chromatography resin with high selectivity for AAT. It can be used for purifying human AAT from plasma (including Cohn fractions), as well as from recombinant or transgenic sources. In a first capture step, Alpha-1 Antitrypsin Select gives high purity and yield. The resin can also be used in intermediate purification/polishing to enhance product purity.
• Matrix: Highly cross-linked spherical agarose
• Average particle size: ~75 μm
• Ligand: Alpha-1 antitrypsin binding ligand
• Ligand density: Approx. 5.5 mg/ml of medium
• Dynamic binding capacity: Approx. 10 mg alpha-1 antitrypsin/mL resin
• Chemical stability: Stable in commonly used aqueous buffers
• pH working range: 3–10
• CIP stability: 2–11
• Storage: 20% ethanol in water
• Pack size: 25 mL
• BioProcess resin: Yes