Magnetic Beads

Introduction of Magnetic Beads

With the rapid development of the biological industry in recent years, protein purification is a key step in scientific research. Compared with the traditional chromatography method, a new method for high-throughput protein purification has recently been introduced - the magnetic beads (MBs) purification method. MBs are versatile tools for the purification, detection, and quantification of analytes in complex matrices in biological experiments and scientific research. The superparamagnetism of MB makes it suitable for various analytical applications, especially for proteins. The principle is to use the affinity groups on the surface of MBs to specifically bind the target protein to achieve selective enrichment of the target protein.

Fig 1. Scheme of MagExo for EV extraction. (Fang X, et al., 2021)

At present, MBs commonly used in laboratories are mainly combined with His tags, glutathione S-transferase tags, and Fc tags to achieve selective enrichment of different proteins.

Types of Our Products

• Protein A/G MBs
• Ni-NTA MBs
• COVID-19 Spike S1 MBs
• Glutathione MBs

Advantages of Our Products

• High selectivity
• Simple steps
• High flexibility and reliability
• Quick response
• High throughput and higher efficiency
• High product purity and high recovery

Due to their ability to separate and precipitate beads using magnetic force, MBs can save experimental time in various fields.

Applications of Our Products

• Quick isolation of antibodies from sera and ascites fluids
• Purification of scFc fragments from cell cultures
• Depletion of unwanted antibodies and fragments from the sample
• Immunocapture, cell-stimulating, biopanning, and flow cytometry

Creative BioMart can provide you with a variety of high-quality magnetic beads for the purification and separation of high-purity recombinant proteins in a series of life science researches such as drug screening, cell biology research, and proteomics. You can quickly find the reagents you need by searching keywords such as CAT number or product name. Please tell us your product needs, we will provide you with a comprehensive consultation. If you have any questions, please feel free to contact us.

*If your organization requires the signing of a confidentiality agreement, please contact us by email.

Reference:

1. Fang X, Chen C, Liu B, et al. (2021) A magnetic bead-mediated selective adsorption strategy for extracellular vesicle separation and purification. Acta Biomaterialia. 124: 336–347.