Benzamidine Affinity Resin

• Product Overview: This affinity resin is prepared by immobilizing p-aminobenzamidine on 4% cross-linked agarose, commonly used for purification or removal of serine proteases from biological samples. Benzamidine derivatives act as broad-spectrum inhibitors for serine proteases such as trypsin, thrombin, urokinase, kallikrein, and pre-kallikrein.
• Matrix: 4% Highly cross-linked agarose
• Appearance: White paste, may separate upon standing
• Wet Particle Size Range: 45–165 μm
• Ligand: p-Aminobenzamidine
• Dynamic binding capacity: ≥ 35 mg Trypsin / mL packed resin
• Coupling chemistry: Epoxy chemistry with p-aminobenzamidine
• pH working range: 2–8
• pH CIP range: 1–9
• Chemical stability: Stable in common aqueous solutions: 8 M urea, 6 M guanidine HCl, hydrochloric acid solution (pH 1–4), 0.025 M Borax solution (pH 8–11)
• Maximum operating pressure: 0.3 MPa
• Maximum flow velocity: > 150 cm/h
• Pack size: 25 mL; 100 mL; 500 mL; 1 L; 5 L; 10 L
• Product features: p-Amino benzamidine ligand affinity resin.
  Used for serine protease purification or removal from biological samples.
  Broad inhibition spectrum: trypsin, thrombin, urokinase, kallikrein, etc.
  Industrial-scale serine protease removal.