Capto Q ImpRes resin

• Cat#No#: Ca-442C
• Product Overview: By combining high-flow characteristics of Capto with a small particle size, Capto Q ImpRes delivers high resolution and excellent pressure-flow properties.
• Description: Capto Q ImpRes is strong cation and strong anion exchangers for the high-throughput intermediate purification and polishing steps of a wide range of biomolecules. Both chromatography media (resins) are part of platform of high-resolution media based on the Capto product line.
  By combining the high-flow characteristics of Capto media with a small particle size, Capto Q ImpRes deliver excellent pressure-flow properties with excellent resolution. The ability to run at higher flow rates and higher bed heights increases productivity and flexibility in process design.
• Characteristic: High-resolution intermediate purification and polishing based on the well-established Capto platform with traditional ligands.
  Flexible process design due to large operational window of flow rates and bed heights.
  High-throughput purifications easy to optimize and scale up.
  Higher manufacturing productivity enables improved process economy.
  Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.
• Maximum operating pressure: 300 kPa at min. 220 cm/h, 1 m diameter column.
• Metal ion capacity: 0.15-0.18 mmol Cl-/ml medium
• Matrix: High-flow agarose
• Particle Size: 36-44 μm
• Average particle size: 40 μm
• Ligand: Quaternary amine
• Dynamic binding capacity: > 55 mg BSA, > 48 mg β-lactoglobulin
• Recommended flow rate: At least 220 cm/h in a 1 m diameter column with bed height 20 cm at 20°C; measured using process buffers with the same viscosity as water at < 3 bar (0.3 MPa, 43.5 psi).
• Recommended column height: 20 cm
• Chemical stability: Commonly used aqueous buffers, 1 M NaOH, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol and 70 % ethanol.
• pH working range: 2–12
• CIP stability: 2–14
• Temperature stability: 4°C to 30°C
• Storage: 4 to 30°C, 20% Ethanol
• Cleaning-in-place: 1 M NaOH, 2 M NaCl, and 70% ethanol
• Sanitization: 0.5 M to 1.0 M NaOH
• Pack size: 25 mL
• BioProcess resin: Yes
• Maximum flow velocity: 4 mL/min (HiTrap 1 mL), 20 mL/min (HiTrap 5 mL).
• Dimensions: 0.7 × 2.5 cm (HiTrap 1 mL), 1.6 × 2.5 cm (HiTrap 5 mL).
• Column volume: 1 mL and 5 mL
• Column hardware pressure limit: 5 bar (0.5 MPa, 70 psi)
• Functional group: –CH2 N+ ( CH3 ) 3