Capto Q XP resin

• Cat#No#: Ca-443C
• Product Overview: Capto Q XP is designed for capture and intermediate purification of large biomolecules, such as immunoglobulins IgG, IgM, IgA, in downstream processes.
• Description: Capto Q XP is a strong anion exchange resin designed for the purification of large biomolecules such as immunoglobulins (e.g., IgG, IgM, IgA) from plasma.
• Characteristic: Efficient industrial-scale purification based on the well-established Capto platform with traditional ligands.
  Flexible process design due to large operational window of flow rates and bed heights.
  High throughput to improve manufacturing productivity and process economy.
  Excellent chemical stability.
  Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.
• Maximum operating pressure: 0.3 MPa at 700 cm/h, 1 m diameter column.
• Metal ion capacity: 95 to 125 µmol Cl-/mL resin
• Matrix: High-flow agarose
• Ionic Exchanger Type: Strong anion exchanger
• Average particle size: ~75 μm
• Ligand: -OCH2CH(OH)CH2OCH2CH(OH)CH2N(CH3)3
• Recommended flow rate: Up to 300 cm/h in a 1 m diameter column with bed height 20 cm at 20°C; measured using process buffers with the same viscosity as water at < 3 bar (0.3 MPa).
• Recommended column height: 20 cm
• Chemical stability: Commonly used aqueous buffers: 1 M sodium hydroxide, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol.
• pH working range: 2–12
• CIP stability: 2–14
• Shelf life: 5 years
• Storage: 20% ethanol at 4°C to 30°C
• Cleaning-in-place: 1 M NaOH, 2 M NaCl, and 70% ethanol
• Sanitization: 0.5 to 1.0 M NaOH
• Pack size: 25 mL
• BioProcess resin: Yes
• Functional group: –CH2 N+ ( CH3 ) 3