| Product Information | |
| Cat#No# | MCdex-01G |
| Product Overview | Gamma-sterilized and ready to use for quick culture start-up. Delivered in a convenient, single-use container system for easy transfer to various cell culture vessels. Supplied dry to save storage space and facilitate transportation. Enable culturing of anchorage-dependent cells in single-use bioreactor to eliminate the need for cleaning and cleaning validation. Supported by extensive product documentation to facilitate regulatory filing. Serum-free function testing to ensure performance. |
| Form | sterilized, dry power |
| Characteristic | CBMC-MCdex1 Gamma is based on a cross-linked dextran matrix which is substituted with positively charged N, N-diethylaminoethyl groups. The charged groups are distributed throughout the microcarrier matrix and the resin has an ionic capacity of 1.4 to 1.6 mmol Cl- /g of resin. |
| Applications | Microcarrier-based culturing can be performed in simple shaker flasks or roller bottles as well as in more advanced traditional or single-use bioreactor systems, from milliliter to thousands-of-liter scales. Compared with cultivation in several shake flasks or roller bottles, one single bioreactor culture allows: Automatic control of pH and dissolved oxygen (DO), in-line cell counting, and logging of cell culture data for product documentation. Perfusion culturing to high cells densities, minimizing the need for several intermediate seed train bioreactors during scale-up. Scaling to be performed in one bioreactor system. Inactivation of harmful organisms in the entire culture batch to be performed in just one step. |
| Quality control analysis | Performance of CBMC-MCdex1 Gamma is validated with serum free medium. Every batch conforms to stringent specifications. Quality control tests are performed to satisfy both physiochemical and functional (i.e., cell growth) properties. |
| Swelling | 20 ml/g |
| Shelf life | The shelf life of CBMC-MCdex1 Gamma is two years. |
| Approximate Surface Area Dry Weight | 0.44 m2/g |
| Approximate Number of Micro-Carriers Dry Weight | 4.3 × 10^6 |
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