Chirality is a fundamental characteristic of biological systems and a long-standing mystery in life science. Nucleic acids, proteins, and polysaccharides all possess chiral structures. Pharmaceutical agents also exist in chiral forms, where the two enantiomers often exhibit different metabolic pathways and pharmacological activities. Regulatory agencies require that drug labeling clearly quantify the efficacy and toxicology of each enantiomer. When significant differences exist, the drug must be marketed in optically pure form. Chromatography has become the method of choice for chiral drug analysis and preparation due to its high efficiency and convenience.
Average particle size
5/10 μm
Phase
Amylose tris [(S)-α-methylbenzylcarbamate]
Product features
o-Chloromandelic acid, abscisic acid, aminoglutethimide, disopyramide, cyclopenthiazide, glutethimide, hexobarbital, imazalil, ketamine, pentobarbital, and related compounds.