Core-Shell Multimodal Flow-Through Resin 700 kDa

• Product Overview: Core-Shell Multimodal Flow-Through Resin 700 kDa is a multimodal resin with a core–shell bilayer structure. The inert shell has a thickness of ~5 μm and functions as a gel filtration layer with a globular protein exclusion limit of ~700 kDa. During purification, target molecules are unable to penetrate the bead interior and flow through, while the core is functionalized with n-octylamine ligands that are hydrophobic and positively charged, binding as many non-target molecules as possible via multimodal interactions to widen the operational window. Core-Shell Multimodal Flow-Through Resin 700 kDa is widely used for purifying large biomolecules such as exosomes, plasmid DNA, and viral particles. Compared with conventional gel filtration resins, Core-Shell Multimodal Flow-Through Resin 700 kDa can provide substantially higher throughput than conventional SEC resins.
• Matrix: Highly rigid agarose
• Average particle size: ~90 μm
• Ligand: n-Octylamine, 20–50 µmol/mL
• pH working range: 3–12
• Chemical stability: Stable in common aqueous solutions: 1 M NaOH, 8 M urea, 6 M guanidine HCl, 70% ethanol, 30% isopropanol, etc.
• Maximum operating pressure: 0.5 MPa
• Maximum flow velocity: 1500 cm/h
• Storage: 2–30 °C in 20% ethanol
• Shelf life: 5 years