IgM Capture Resin (High Performance)

• Product Overview: This thiophilic affinity resin is made by coupling 2-mercaptopyridine to fine, high-rigidity agarose beads. Its optimized ligand density provides suitable affinity for IgM, and the fine beads enhance binding capacity for large IgM molecules. The principle relies on electron donor-acceptor interactions, which are stronger in high-salt and weaker in low-salt conditions.
• Matrix: 6% Highly cross-linked agarose
• Appearance: White paste, may separate upon standing
• Average particle size: 34 μm
• Wet Particle Size Range: 24–44 μm
• Ligand: 2-Mercaptopyridine
• Dynamic binding capacity: ~5 mg Human IgM / mL resin
• Coupling chemistry: Epoxy chemistry
• pH working range: 3–11
• pH CIP range: 2–13
• Chemical stability: Stable in common aqueous solutions: 70% ethanol, 30% isopropanol, 1 M acetic acid, 0.1 M NaOH
• Maximum operating pressure: 0.3 MPa
• Pack size: 25 mL; 100 mL; 500 mL; 1 L; 5 L; 10 L
• Storage: 2–30 °C in 20% ethanol or 2% benzyl alcohol
• Product features: Thiophilic affinity resin with 2-mercaptopyridine ligand.
  Optimized ligand density for IgM capture with high binding capacity.
  High-rigidity agarose matrix for efficient large-molecule purification.