Mag Sepharose PrismA magnetic bead resin

• Cat#No#: Ma-335C
• Product Overview: Mag Sepharose PrismA magnetic bead resin uses a genetically engineered protein A-derived ligand immobilized to Mag Sepharose beads for capture of target proteins followed by collection of the beads using a magnetic device.
  Can be used for high-throughput screening of antibody drug candidates in microwell plates and for purification of antibodies in a magnetic separator.
  Magnetic properties that reduce materials and workload for antibody screening in microwell plates.
  Capture of mAbs in up to 80 L of unfiltered feed eliminates clarification steps in antibody processes.
  Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH for improved process economy and robustness.
• Description: Mag Sepharose PrismA magnetic bead resin is designed to simplify enrichment of antibodies by immunoprecipitation. The technology uses a genetically engineered protein A-derived ligand immobilized to Mag Sepharose beads for capture of target proteins followed by collection of the beads using a magnetic device. Mag Sepharose PrismA resin can be used for highthroughput screening of antibody drug candidates in microwell plates and for purification of antibodies in a magnetic separator.
• Characteristic: Magnetic properties that reduce materials and workload for antibody screening in microwell plates.
  Capture of mAbs in up to 80 L of unfiltered feed eliminates clarification steps in antibody processes.
  Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH for improved process economy and robustness.
• Matrix: Paramagnetic, spherical, highly cross-linked agarose particles
• Average particle size: 37–100 μm
• Ligand: Alkaline-stabilized protein A-derived (E.coli).
• Ligand density: > 15 mg/mL
• Dynamic binding capacity: Typically, > 100 mg IgG/mL resin
• Chemical stability: Stable in commonly used aqueous buffers used in purification of mAbs.
• pH working range: 3–12
• CIP stability: 2–14
• Storage: 20% ethanol, 4°C to 8°C
• Shipping: 20% ethanol
• Sanitization: 2% Hibitane/20% Ethanol or with 70% Ethanol.
• Pack size: 25 mL