Similar to other products in this series, multimodal cation exchange resin is a weak cation exchange medium with phenyl-carboxyl groups coupled to high-rigidity agarose beads. It tolerates higher salt concentrations, eliminating the need for sample desalting, suitable for broad IEC applications.
Matrix
High-rigidity agarose
Appearance
White paste, may separate upon standing
Average particle size
75 μm
Ligand
Multimodal weak cationic groups
Dynamic binding capacity
> 28 mg BSA / mL packed resin (30 mS/cm)
Coupling chemistry
Multimodal functionalization (phenyl-carboxyl)
pH working range
3–12
pH CIP range
3–14
Chemical stability
Stable in common aqueous solutions: 1 M NaOH, 1 M acetic acid, 6 M guanidine HCl, 8 M urea, 70% ethanol, 30% isopropanol, 20% ethanol, 2% benzyl alcohol
Maximum operating pressure
0.5 MPa
Pack size
25 mL; 100 mL; 500 mL; 1 L; 5 L; 10 L; 20 L; 40 L
Product features
Multimodal weak cation exchange resin; multimodal ligand provides salt tolerance under high conductivity; uses high-rigidity agarose matrix, offering high throughput and high selectivity; high dynamic binding under high conductivity; widely suitable for medium purification of antibodies and recombinant proteins, removing aggregates and fragments.