PreDictor Capto MMC ImpRes

• Cat#No#: Pr-294P
• Product Overview: PreDictor plates are disposable, 96-well filter plates for parallel screening of resins and chromatographic conditions such as binding, wash, and elution conditions. Screen different chromatography resins simultaneously using dedicated screening plates, or more thoroughly using plates containing a single resin. Different applications require different amounts of resins in the wells, and we offer a wide range of PreDictor plates containing different chromatography resins at different volumes. Data generated using PreDictor plates show good correlation with data from chromatography columns, making the plates an excellent tool for initial screening of process conditions.
• Characteristic: Supports high-throughput process development (HTPD) by allowing parallel screening of chromatographic conditions using a 96-well plate format.
  Allows fast and efficient evaluation of parameters for binding/wash/elution conditions, and chromatography resin benchmarking.
  Results show good correlation with data obtained by column chromatography.
  Each well is prefilled with defined amounts of Capto MMC ImpRes.
  Can be used with centrifugation or vacuum, manually or in automated robotic systems.
  Assist software supports the PreDictor workflow from set-up of experimental design to data evaluation.
• Maximum operating pressure: 0.3 MPa (3 bar, 43.5 psi) at min. 220 cm/h, 1 m diameter column, 20 cm bed height
• Metal ion capacity: 25 to 39 µmol/mL
• Matrix: High-flow agarose
• Ionic Exchanger Type: Multimodal weak cation exchanger
• Average particle size: 36 to 44 μm
• Dynamic binding capacity: 60 to 90 mg MAb/mL (residence time 4 to 5 min)
• Chemical stability: All commonly used aqueous buffers, 1 M NaOH, 2 M NaCl, 5% 1-propanol, 30% isopropanol, 70% ethanol.
• pH working range: 3 to 12
• CIP stability: 2 to 14
• Storage: 4 to 30°C, 20% Ethanol
• Pack size: 6 μl
• Dimensions: 127.8 x 85.5 x 30.6 mm
• Number of wells: 96
• Material: Polypropylene (PP) and Polyethylene (PE)
• Resin suspensions in total volumes: 200 μl for 2 μl sedimented medium/well 500 μl for 6, 20, and 50 μl sedimented medium/well For PreDictor isotherm plates: – 500 μl for 50 μl sedimented medium/well – 200 μl for 20 μl sedimented medium/well – 500 μl for 8 μl sedimented medium/well – 375 μl for 6 μl sedimented medium/well – 250 μl for 4 μl sedimented medium/well – 125 μl for 2 μl sedimented medium/well.
• Centrifugation force recommended: 100 x g (Sample Dependent)-500 x g (Sample Dependent)
• Centrifugation force max.: 700 x g
• Operating temp. max.: 30°C
• Operating temp. min.: 4°C