Reversed-Phase Silica, PFP

• Product Overview: Reversed-phase chromatography silica gel features highly uniform particle size, narrow pore size distribution, high mechanical strength, high bonding density, and favorable end-capping. These properties deliver robust physical and chemical performance including easy column packing, high column efficiency, high resolution, low back pressure, and wide pH tolerance, with minimal bonded phase bleed. The result is high loading capacity, favorable selectivity, good resolution, high efficiency, long column lifetime, and low purification cost.
  The comprehensive product range meets the requirements of both analytical UPLC/HPLC and preparative HPLC (Prep-HPLC), and is widely used for chromatographic analysis and industrial production of organic compounds, natural products, fermentation and semi-synthetic antibiotics, and protein macromolecules.
  Available bonded phases include C1, C4, C8, C18, C18 AQ, C18 Polar, C30, Phenyl, and others, to meet reversed-phase analysis and preparative separation needs for various sample types. Custom products available for specialized applications.
• Matrix: High-purity silica
• Average particle size: 10 µm
• Pore Size (Å): 120
• Surface area: ~310 m²/g
• Ligand: Pentafluorophenyl (PFP)
• % Carbon: 12%
• pH working range: 2–8
• Bulk density: ~0.50 g/mL
• Product features: Compared to conventional reversed-phase materials, the fluorinated bonded phase provides stronger polar interactions with favorable selectivity for certain polar compounds. Additionally, the fluorinated phase offers some steric selectivity, enabling separation of difficult-to-resolve structural isomers.