IEC is highly effective for biomolecule separation using charge interactions. high-flow strong anion exchanger couples quaternary ammonium groups onto fine high-rigidity agarose microspheres, forming a strong anion exchanger with higher resolution than standard resins, suitable for fine or moderate purification steps.
Matrix
High-rigidity agarose
Appearance
White paste, may separate upon standing
Wet Particle Size Range
36–44 μm
Ligand
Quaternary ammonium
Dynamic binding capacity
> 50 mg β-Lactoglobulin / mL packed resin
Coupling chemistry
Quaternary ammonium functionalization
pH working range
2–12
pH CIP range
2–14
Chemical stability
Stable in common aqueous solutions: 1 M NaOH, 1 M acetic acid, 70% ethanol, 20% ethanol, 30% isopropanol, 6 M guanidine HCl, 8 M urea, 100 mM thioglycerol + 25 mM Tris pH 8.5, 0.1 M citric acid + 8 M urea + 1 M NaCl pH 2.5, 0.1 M citric acid + 8 M urea pH 2.5
Maximum operating pressure
0.5 MPa
Maximum flow velocity
≥ 450 cm/h
Pack size
25 mL; 100 mL; 500 mL; 1 L; 5 L; 10 L; 20 L; 40 L
Product features
High-resolution strong anion exchange resin; uses high-rigidity, high-resolution agarose matrix; suitable for medium or fine purification of large-scale samples in industrial production; stable physical and chemical properties with long service life; widely applied for separation/purification of proteins, nucleic acids, and peptides in biopharmaceuticals and bioengineering.