IEC relies on charge interactions for biomolecule separation, offering high binding capacity and resolution. strong anion exchanger couples quaternary ammonium groups onto high-rigidity agarose microspheres, forming a strong anion exchanger with higher pressure tolerance and binding capacity than Q highly cross-linked agarose.
Matrix
High-rigidity agarose with dextran chains
Appearance
White paste, may separate upon standing
Average particle size
90 μm
Ligand
Quaternary ammonium
Dynamic binding capacity
> 100 mg BSA / mL packed resin
Coupling chemistry
Quaternary ammonium functionalization
pH working range
2–12
pH CIP range
2–14
Chemical stability
Stable in common aqueous solutions: 1 M NaOH, 1 M acetic acid, 70% ethanol, 20% ethanol, 6 M guanidine HCl, 8 M urea
Maximum operating pressure
0.5 MPa
Maximum flow velocity
≥ 1500 cm/h
Pack size
25 mL; 100 mL; 500 mL; 1 L; 5 L; 10 L; 20 L; 40 L
Product features
Strong Anion Exchange Resin with quaternary ammonium (Q) ligand; high-rigidity agarose matrix with low back pressure, suitable for rapid capture of large-scale samples; good physical and chemical stability, low non-specific adsorption; widely applied for large-scale separation/purification of recombinant proteins in biopharmaceuticals and bioengineering.