Antibody-optimized strong cation exchanger couples cationic ligands onto fine high-rigidity agarose microspheres, forming a strong cation exchanger with high binding capacity and resolution, suitable for fine or moderate purification, favorable for monoclonal antibody isoform separation, aggregate removal, ADC post-conjugation purification, and multi-antibody/recombinant protein purification.
Matrix
High-rigidity agarose
Appearance
White to off-white paste, may separate upon standing
Average particle size
60 μm
Ligand
Sulfopropyl (SP)
Dynamic binding capacity
≥ 100 mg IgG / mL packed resin
Coupling chemistry
Sulfopropyl functionalization
pH working range
4–12
pH CIP range
3–14
Chemical stability
Stable in common aqueous solutions: 1 M NaOH, 6 M guanidine HCl, 30% isopropanol, 70% ethanol
Maximum operating pressure
0.5 MPa
Maximum flow velocity
100–300 cm/h
Pack size
25 mL; 100 mL; 500 mL; 1 L; 5 L; 10 L; 20 L
Storage
2–30 °C in 20% ethanol or 2% benzyl alcohol
Product features
Agarose matrix cation exchange resin; high-rigidity, high-resolution agarose matrix; suitable for high flow, efficient processing of large-volume feed; high capacity and high resolution, adaptable to different sample purification needs; widely applied for intermediate or fine purification of monoclonal antibodies, bispecific antibodies, antibody fragments, ADCs, and Fc-fusion proteins.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!