Strong Cation Exchange Resin (Polymeric)

• Product Overview: Strong Cation Exchange Resin (Polymeric) is a strong cation exchange medium based on cross-linked polystyrene-divinylbenzene matrix, with surface-bonded sulfonylpropyl functional groups. Special pore design allows high flow rate without compromising binding capacity or resolution, enabling rapid interaction between biomolecules and functional groups. Features include high mechanical strength, enhanced interactions, high capacity and resolution, and chemical/physical stability.
• Matrix: Cross-linked PS-DVB beads
• Appearance: White paste, may separate upon standing
• Average particle size: ~50 μm
• Ligand: Sulfopropyl (SP)
• Dynamic binding capacity: > 100 mg Human IgG / mL packed resin
• Coupling chemistry: Sulfopropyl (SP) functionalization
• Chemical stability: Stable in common aqueous solutions: water, 1 M NaOH, 8 M urea, 6 M guanidine HCl, ethylene glycol, 0-100% ethanol, acetonitrile, 2 M acetic acid, 1 M hydrochloric acid, other common organic solvents
• Maximum operating pressure: 10 MPa
• Pack size: 25 mL; 100 mL; 500 mL; 1 L; 5 L; 10 L; 20 L; 40 L
• Storage: 2–30 °C in 20% ethanol or 0.1 M NaOH
• Product features: Polymer matrix/base cation exchange resin; high capacity and salt tolerance; adaptable to different purification needs, reduces sample dilution, improves purification efficiency; high resolution; widely applied for intermediate or fine purification of monoclonal antibodies, bispecific antibodies, ADCs, and other biomolecules.