Weak Cation Exchange Resin (Dextran)

• Product Overview: Carboxymethyl (CM) cross-linked dextran C-25 couples carboxymethyl groups onto cross-linked agarose microspheres, forming a weak cation exchanger. Retains favorable hydrophilicity and pore structure, compatible with bioactive molecules, minimal nonspecific adsorption. Ideal for small molecules like antibiotics and natural products. Not suitable for fixed-bed columns due to volume changes in different buffers.
• Matrix: Cross-linked dextran
• Appearance: White to slightly yellow powder
• Wet Particle Size Range: 40–120 μm
• Ligand: Carboxymethyl (CM)
• Capacity: 4.0–5.0 mmol H⁺/g dry powder
• pH working range: 2–12
• pH CIP range: 2–13
• Chemical stability: Stable in common aqueous solutions: 8 M urea, 6 M guanidine HCl, 30% isopropanol, 70% ethanol
• Maximum operating pressure: 0.3 MPa
• Pack size: 25 g; 100 g; 500 g; 1 kg; 5 kg; 10 kg; 20 kg; 25 kg
• Product features: Weak cation exchange resin with Carboxymethyl (CM) ligand; cross-linked dextran matrix/base; extremely low non-specific adsorption; high capacity for small molecules; ideal for separation/purification of antibiotics and natural products.