Creative BioMart Chromatography provides method development and optimization services for isolation and purification. Separation and purification is the core of many processes. It is the technical basis for determining the safety, efficacy, yield and cost of products. Compared with other separation and purification technologies, preparation chromatography is easier to achieve the desired product purity, but its cost is relatively higher. Therefore, the development and optimization of chromatographic purification method plays an important role in improving product quality and controlling production cost.
Technical Advantages
- According to customers' process requirements, comprehensively evaluate and optimize various platforms of separation and purification techniques.
- A variety of separation and analysis systems are available.
- Screen the most suitable packing materials from our extensive product library.
- Custom chromatography columns and custom resins to achieve the optimization of process performance
--- High Performance Flash Chromatography (HPFC) - Widely used in crude separation of natural products, fermentative drugs and synthetic products.
--- Prep-HPLC with DAC column - Used for industrial production of APIs and fine separation of natural products, which solves the problem that traditional silica gel column can't pass the EIA requirement for environmental pollution.
--- Simulated moving bed (SMB) chromatography - To maximize the efficiency of column separation, daily production up to several kilograms.
--- Multi Chromatography Purification System (MCP) – Used for fermentation products with functions of filtration, enrichment, fine separation, detection and collection.
--- Include but are not limited to HPLC, ICP-OES, ICP-MS, GC, GC/MS, LC/MS, SFC, RPLC, UPLC, Accurate Mass MS, etc.
--- Normal phase - regular silica, deactivated silica, NH2, Aluminum, etc. It is most commonly used in the separation of natural products, polar complex of small molecules and isomer.
--- Reversed phase - C18, C8, C4,Phenylc, etc. It allows extremely polar and non-polar compounds to be analyzed in a single run.
--- Ion exchange resin - SCX, SAX, WCX, WAX.
--- Polar-modified bonded phase – C1, C2, etc.
Creative BioMart Chromatography has rich experience in method development in the field of separation and purification. We provide optimization services to existing methods to improve purity and yield and further save costs. It also provides the development of new methods. We are familiar with the performance of various types of chromatography columns and packing materials, and aiming to customize the most suitable process for you to help your R&D and production. Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our services, please contact us.
How to Place an Order
*If your organization requires the signing of a confidentiality agreement, please contact us by email.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.